The Ultimate Guide to CJC-1295 with DAC (Dosing, Benefits, Side Effects, and More!)

In this article we will dive into..

• How CJC-1295 with DAC works in the body
• What is DAC?
• CJC vs Growth Hormone
• Benefits of CJC
• Side Effects of CJC
• Dosing of CJC

And much more…..

Introduction

CJC-1295 is a synthetic peptide hormone analog that has gained popularity in the field of bodybuilding, anti aging, and biohacking. 

 It is primarily known for its ability to boost growth hormone (GH) levels in the body, providing tons of benefits for the user including things like better skin, muscle growth, and better fat loss. 

This article delves into the origins, mechanisms, benefits, side effects, and proper usage of CJC-1295.

Origins of CJC-1295

CJC-1295 was developed by ConjuChem Biotechnologies, a Canadian biotechnology company, in the early 2000s. 

The primary goal was to create a compound that could stimulate the release of growth hormone (GH) by acting on the pituitary gland. 

CJC-1295 is a tetrasubstituted peptide, meaning it has four specific amino acid substitutions that enhance its stability and efficacy.

What is DAC?

A common question many people ask regarding CJC is what is DAC? The DAC stands for Drug Affinity Complex. 

These exist to help protect against peptide degradation and to help extend the half life by stopping them from being quickly removed by the kidneys. 

Mechanism of Action

CJC-1295 belongs to a class of compounds known as growth hormone-releasing hormone (GHRH) analogs. 

It works by mimicking the action of the natural GHRH, which stimulates the pituitary gland to produce and release GH. 

However, what sets CJC-1295 apart from other GHRH analogs is its extended half-life.  The extended half life allows for easier usage of the compound. 

Benefits of CJC-1295

CJC comes with a multitude of benefits that users of all kinds can enjoy.  While not all here is a list of the major ones. 

1. Increased Growth Hormone Levels: The primary benefit of CJC-1295 is its ability to significantly increase GH levels in the body, which can enhance various physiological functions. Higher growth hormone levels can help improve everything from building muscle, to helping the brain, to helping recover from injuries. 
2. Improved Muscle Growth and Recovery: Elevated GH levels promote protein synthesis, leading to increased muscle mass and faster recovery after workouts.
3. Enhanced Fat Loss: GH promotes lipolysis, the breakdown of fat, making it easier to lose body fat while maintaining lean muscle mass.
4. Anti-Aging Effects: Higher GH levels are associated with improved skin elasticity, reduced wrinkles, and overall rejuvenation.
5. Improved Sleep: GH has a positive impact on sleep quality, particularly deep sleep stages, which are crucial for recovery and overall health.
6. Bone Density: GH stimulates the production of bone-forming cells, potentially increasing bone density and reducing the risk of osteoporosis.
7. Improved Hair and Skin Health: CJC through raising growth hormone levels is able to help improve both skin and hair health.  Your hair will grow faster and you will notice a certain glow in your skin. 
8. Improved Sleep: Oftentimes raising growth hormone can also help to improve one’s sleep quality. 
9. No Hunger: Unlike other products that can boost ones growth hormones levels like Mk677, CJC will not give you ravenous hunger as a side effect. 

Side Effects of CJC-1295

While CJC-1295 offers numerous benefits, it is not without potential side effects. These can vary depending on individual responses and dosages:

1. Injection Site Reactions: Pain, redness, or swelling at the injection site is a common side effect.
2. Flu-Like Symptoms: Some users report experiencing flu-like symptoms, such as fatigue, muscle aches, and headaches.
3. Water Retention: Increased water retention and bloating can occur, especially at higher doses.
4. Carpal Tunnel Syndrome: Prolonged use of GH-releasing peptides can lead to symptoms of carpal tunnel syndrome, including numbness and tingling in the hands.
5. Increased Blood Glucose Levels: Elevated GH levels can lead to an increase in blood sugar, which is why you should consider pairing your CJC with something like Berberine. 
6. Nausea: Some users may experience nausea or gastrointestinal discomfort.
7. Increase in Prolactin: Some users get higher prolactin levels with the increase in growth hormone levels. 

CJC vs Growth Hormone

Many people oftentimes also ask about the difference in using Growth Hormone vs CJC.

Growth Hormone is a fantastic option but CJC allows for some benefits over the standard growth hormone therapy like….

1. More Cost Effective: Oftentimes CJC is less expensive than growth hormone. 
2. Less Pinning: CJC can only be pinned once or twice per week creating a dosing schedule that is much easier to adhere to. 
3. Easier to Source: CJC can be easier to find and source then real growth hormone. 

Dosing Protocols

The optimal dosing of CJC-1295 can vary based on individual goals and responses. However, general guidelines are as follows:

1. Frequency: Due to its long half-life, CJC-1295 with DAC can be administered once or twice per week.
2. Dosage: Typical dosages range from 1 mg to 2 mg per injection. Beginners are often advised to start at the lower end to assess tolerance.
3. Injection Method: CJC-1295 is typically administered via subcutaneous injection, meaning it is injected into the fatty tissue just beneath the skin.
4. Cycle Length: Common cycle lengths range from 8 to 12 weeks, followed by a break to prevent desensitization and maintain effectiveness.
5. Ancillaries: Common ancillaries that should be run with CJC are berberine (for blood glucose), dandelion root (for water retention), and P5P (raise in prolactin). 

Read also about Mk-677

Compounds to Stack with CJC-1295

CJC can be stacked with the following compounds to make for a more synergistic cycle experience.

1. Mk677: Due to them working through two different pathways CJC can be taken with Mk677 to help the body produce even more growth hormone. 
2. Growth Hormone: Many users have found that stacking growth hormone and CJC together can lead to some insane gains. 
3. Sarms: CJC can pair really well with sarm cycles and help the user take their sarm cycle to the next level. 

How to Use CJC-1295

1. Preparation: Reconstitute the lyophilized (freeze-dried) CJC-1295 powder with bacteriostatic water. This involves gently injecting the water into the vial containing the powder and allowing it to dissolve.
2. Administration: Use an insulin syringe for precise dosing. Clean the injection site with an alcohol swab, pinch the skin, and insert the needle at a 45-degree angle.
3. Post-Injection: After injecting, apply slight pressure to the injection site to minimize bleeding or bruising.

Conclusion

CJC-1295 is a potent peptide that can offer numerous benefits, particularly for those looking to enhance muscle growth, fat loss, and overall anti-aging effects.

Understanding the compound can be crucial in creating a safe cycle that is not only optimized for your gains but also for your health.

 While CJC does come with side effects by understanding the product and the mechanisms through which it works you can help to combat nearly all of the side effects.

If you have stuck around till this part then congrats you are a CJC expert and ready to start your CJC cycle!

Works Cited

1. Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006 Mar;91(3):799-805. doi: 10.1210/jc.2005-1536. Epub 2005 Dec 13. PMID: 16352683.
2. Alba M, Fintini D, Sagazio A, Lawrence B, Castaigne JP, Frohman LA, Salvatori R. Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse. Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1290-4. doi: 10.1152/ajpendo.00201.2006. Epub 2006 Jul 5. PMID: 16822960.
3. Sackmann-Sala L, Ding J, Frohman LA, Kopchick JJ. Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects. Growth Horm IGF Res. 2009 Dec;19(6):471-7. doi: 10.1016/j.ghir.2009.03.001. Epub 2009 Apr 21. PMID: 19386527; PMCID: PMC2787983.
4. Ionescu M, Frohman LA. Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab. 2006 Dec;91(12):4792-7. doi: 10.1210/jc.2006-1702. Epub 2006 Oct 3. PMID: 17018654.
5. https://academic.oup.com/jcem/article/91/3/799/2843281